Shop Products that Heal Wounds
Donell brings targeted scientific discoveries to formulations that are unsurpassed in the market place.
Skin that undergoes treatments from chemical peels, microdermabrasion, laser treatment, radiation therapy, and plastic surgery benefit tremendously from the healing and anti-inflammatory benefits of Donell’s physician-recommended products.
TOPICAL WOUND HEALING
Dr. Prudden’s initial studies showing the acceleration of wound healing in the presence of MCC were followed up in studies by Prudden and other investigators. Among them was an evaluation of the MCC effect on the time course of wound tensile strength as an index of wound healing. It was found that MCC increases the rate of growth as well as the ultimate strength of the wound. It was further demonstrated that the increase in tensile strength of the MCC treated wound is related to the accelerated growth of granulation tissue.
As a topical anti-inflammatory, MCC has been shown to match the efficacy of more potent corticosteroids, but without the side effects and without inhibiting wound healing. Topical corticosteroids are contra-indicated in infective skin diseases.
MCC molecules are effective in treating various inflammatory skin diseases by blocking the inflammatory cascade central to such diseases. They do this by weakening one of the two key signal transduction pathways within cells involved in the cells’ inflammatory response. The fact that MCC affects only part of a cell’s inflammatory response mechanism may explain why it does not have side effects like corticosteroids and other immunosuppressive drugs.
Houck and Vickers have demonstrated that there is an anti-inflammatory activity and acceleration of tissue repair by MCC. Inflammation involves three major changes in dermal chemistry:
The disappearance of stainable acid mucopolysaccharides from the necrotic lesion
The appearance of large amounts of endogenously synthesized glycoprotein in the ground substance of the wound. The loss of large amounts of insoluble collagen from the site of local injury The Houck and Vickers studies show that with the topical application of MCC, the time required to restore dermal chemistry back to normal is reduced by almost 50%.
I have used the treatment Donell Post-Procedure Ointment following CO2 and Erbium laser resurfacing since 2000 and the post operative down time is considerably shortened. Recently a patient came for a second CO2 resurfacing and recovery with Donell Post-Procedure Ointment was 50% less than recovery the first time around with another popular occlusive product.Colonel Garrison V. Morin - USAF MC Chairman Otolaryngology (ENT) Keesler Medical Center MS
I have been using Donell Post-Procedure Ointment since 1996 following laser surgery upon removal of an occlusive dressing at day 5. Donell Post-Procedure Ointment is comfortable for patients and a great wound healer. Further during radiation therapy of a family member it salved the pain and quickly healed the surrounding tissue.S. Larry Schlesinger - MD FACS Maui Plastic Surgery LLC Kahului Maui HI
Donell Skin Savers have solved a lot of problems in our facial rooms where we treat many desert and show biz-worn faces. After all treatments—including acids micro-dermabrasions enzymes and waxing—Donell Correction Cream or Donell Post-Procedure Ointment are used to eliminate irritation redness and dryness. Most patients then go on to use Donell Correction Cream on an every day basis to maintain a healthy appearance.Audrey Miller - Clinical Aesthetician Audrey Miller Skin Care Inc. Las Vegas NV
I have been an Aesthetician for over 20 years working with highly visible dermatologists and since 1991 have used the Donell product line both personally and with patients following procedures and whenever a topical anti-inflammatory is indicated. The products are extremely beneficial for healing and alleviating irritation and pain.Jan Pelletier - Para Medical Aesthetician Dallas TX
Frequently it is dermal recovery in post surgical and laser procedures that is most challenging to the patient and physician. Without question Donell Post-Procedure Ointment Donell Correction Cream and Cream Wash provide the quickest time to recovery excellent patient compliance and an even-toned supple patina to the healed skin. ... The Donell line gives me the greatest confidence that our patients are receiving superb product quality.Michael Stefan - MD Plastic Surgeon Exton PA
We have used Donell Post-Procedure Ointment for many years. Patients have found it to be comfortable and healing during the post-laser period and there have been no allergic reactions.A. Chasby Sacks - MD Arizona Cosmetic Surgery Phoenix AZ